Glossary entry

English term or phrase:

germlined

Portuguese translation:

germinativas

Added to glossary by Maria Teresa Borges de Almeida
Nov 17, 2018 19:33
5 yrs ago
1 viewer *
English term

germlined

English to Portuguese Science Genetics
"The antibodies or antigen binding fragments exhibiting high human homology or having at least one camelid-derived CDR sequence, VH and/or VL domain may be humanised or germlined variants of VH or VL domains from camelid conventional antibodies, wherein the terms “humanised” and “germlined” are as defined elsewhere herein."

"The invention also provides humanised or human germlined variants, affinity variants and variants containing conservative amino acid substitutions, as defined herein."
Proposed translations (Portuguese)
4 +2 germinativas
Change log

Dec 1, 2018 08:54: Maria Teresa Borges de Almeida Created KOG entry

Discussion

Isadora Creio que a expressão correta é germline variants...

Proposed translations

+2
17 mins
Selected

germinativas

Diria assim em PT(pt), ver:

Identification o -E cadherin /CDH1 germline variants and environmental risk factors in early onset gastric cancer patients
Identificação de variantes germinativas no gene E-caderina / CDH1 e de fatores ambientais de risco em pacientes jovens portadores de câncer gástrico
http://www.teses.usp.br/teses/disponiveis/5/5155/tde-0411201...

A penetrância das mutações do CDKN2A é modificada por variantes germinativas de outros genes, incluindo MC1R. Algumas famílias,
portadoras de mutações germinativas do CDKN2A têm também risco elevado de desenvolverem cancro do pâncreas.
https://estudogeral.uc.pt/bitstream/10316/37287/1/Alteracoes...
Peer comment(s):

agree Oliver Simões
43 mins
Obrigada, Oliver!
agree Paulinho Fonseca
1 hr
Obrigada, Paulinho!
Something went wrong...
4 KudoZ points awarded for this answer. Comment: "Selected automatically based on peer agreement."
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